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Kojima Research Group

Kojima Research Group

Circadian rhythmicity is a fundamental aspect of temporal organization in essentially every cell in the body, and modulates much of physiology, biochemistry, and behavior.  In order to maintain daily cycles, cell-autonomous circadian oscillators drive rhythmic expression of approximately 5-10% of mRNAs to ultimately drive a wide range of rhythmic biological processes.

The Kojima lab is interested in understanding 1) how the circadian clock regulates the rhythms of thousands of mRNAs and proteins with the correct period, phase, and amplitude; and 2) how circadian clock utilizes rhythmically expressed proteins to regulate rhythmic physiology and behavior. The lab uses the mouse as an animal model system and integrate diverse approaches - genetics, genomics, bioinformatics, neuroscience, and molecular/cellular biology - to answer these questions.

Principal Investigator

Shihoko Kojima

Shihoko Kojima, Ph.D.

Assistant Professor of Biological Sciences

Fralin Life Sciences Institute 
Steger Hall | Office 245D
1015 Life Science Circle
Blacksburg, VA 24061-0477

Office Phone: (540) 231-5196
Lab Phone:  (540) 231-9539